PROTAC ATR degrader-2, CAS [[3010273-12-5]] Preis auf Anfrage

Produktübersicht

• Artikelname: PROTAC ATR degrader-2, CAS [[3010273-12-5]] Preis auf Anfrage
• Artikelnummer: TGM-T87258
• Hersteller Artikelnummer: T87258
• Alternativnummer: TGM-T87258-10MG,TGM-T87258-50MG
• Hersteller: TargetMol
• Kategorie: Biochemikalien

Produktbeschreibung

PROTAC ATR degrader-2 (Compound 8i) serves as a PROTAC degrader targeting ATR, effectively degrading it in acute myeloid leukemia (AML) cell lines MV-4-11 and MOLM-13, with DC50 values of 22.9 and 34.5 nM, respectively. This compound induces apoptosis and inhibits the proliferation of AML cells. Additionally, PROTAC ATR degrader-2 demonstrates favorable pharmacokinetic properties and potent antitumor activity in a mouse model of AML.

Produkteigenschaften

• Molekulargewicht: 743.81
• CAS Nummer: [3010273-12-5]
• Formel: C40H41N9O6
• Target-Kategorie: Apoptosis|||PROTACs

Bilder

T87258