PROTAC ATR degrader-2, CAS [[3010273-12-5]] Preis auf Anfrage

Product Overview

• Article Name: PROTAC ATR degrader-2, CAS [[3010273-12-5]] Preis auf Anfrage
• Biozol Catalog Number: TGM-T87258
• Supplier Catalog Number: T87258
• Alternative Catalog Number: TGM-T87258-10MG,TGM-T87258-50MG
• Manufacturer: TargetMol
• Category: Biochemikalien

Product Description

PROTAC ATR degrader-2 (Compound 8i) serves as a PROTAC degrader targeting ATR, effectively degrading it in acute myeloid leukemia (AML) cell lines MV-4-11 and MOLM-13, with DC50 values of 22.9 and 34.5 nM, respectively. This compound induces apoptosis and inhibits the proliferation of AML cells. Additionally, PROTAC ATR degrader-2 demonstrates favorable pharmacokinetic properties and potent antitumor activity in a mouse model of AML.

Product Properties

• Molecular Weight: 743.81
• CAS Number: [3010273-12-5]
• Formula: C40H41N9O6
• Target: Apoptosis|||PROTACs

Images

T87258