Pan-RAS-IN-2, CAS [[3034673-92-9]]

Produktübersicht

• Artikelname: Pan-RAS-IN-2, CAS [[3034673-92-9]]
• Artikelnummer: TGM-T88116
• Hersteller Artikelnummer: T88116
• Alternativnummer: TGM-T88116-1MLX10MM(INDMSO),TGM-T88116-1MG,TGM-T88116-5MG,TGM-T88116-10MG,TGM-T88116-25MG,TGM-T88116-50MG
• Hersteller: TargetMol
• Kategorie: Biochemikalien

Produktbeschreibung

Pan-RAS-IN-2 (compound 6A) is an orally active molecular glue that targets RAS by inducing ternary complex formation with cyclophilin A (CYPA) and RAS in the ON state, leading to potent inhibition of downstream RAF binding and pERK signaling with an IC50 of 0.3 nM in AsPC-1 cells, Pan-RAS-IN-2 demonstrates strong antiproliferative effects in RAS-mutant cancer cell lines, supporting research into targeted therapies for colorectal and pancreatic cancers.

Produkteigenschaften

• Molekulargewicht: 837.08
• Reinheit: 99.81%
• CAS Nummer: [3034673-92-9]
• Formel: C46H60N8O5S
• Target-Kategorie: Ras

Bilder

T88116

T88116