CSN5-IN-1 (compound Ac-11) serves as an inhibitor of CSN5, exhibiting IC50 values of 12.56 µM in FP assay and 19 µM in fluorescence assay. Additionally, it influences cellular protein expression by downregulating PD-L1 and upregulating NEDD8-Cul1.
Molekulargewicht:
318.43
Formel:
C17H22N2O2S
Target-Kategorie:
PD-1/PD-L1|||E1/E2/E3 Enzyme|||Others
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
