CSN5-IN-1 (compound Ac-11) serves as an inhibitor of CSN5, exhibiting IC50 values of 12.56 µM in FP assay and 19 µM in fluorescence assay. Additionally, it influences cellular protein expression by downregulating PD-L1 and upregulating NEDD8-Cul1.
Molecular Weight:
318.43
Formula:
C17H22N2O2S
Target:
PD-1/PD-L1|||E1/E2/E3 Enzyme|||Others
* VAT and and shipping costs not included. Errors and price changes excepted
