Autophagyinducer 5 (compound 21o) serves as a potent inhibitor of MCF-7 (IC50: 2 µM), making it a potential candidate for breast cancer therapy. It induces autophagy by activating the ROS/JNK signaling pathway, which increases ROS production and JNK phosphorylation, ultimately exerting cytotoxic effects.
Molekulargewicht:
648.88
Formel:
C41H52N4O3
Target-Kategorie:
Reactive Oxygen Species|||Autophagy|||JNK
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
