Autophagyinducer 5 (compound 21o) serves as a potent inhibitor of MCF-7 (IC50: 2 µM), making it a potential candidate for breast cancer therapy. It induces autophagy by activating the ROS/JNK signaling pathway, which increases ROS production and JNK phosphorylation, ultimately exerting cytotoxic effects.
Molecular Weight:
648.88
Formula:
C41H52N4O3
Target:
Reactive Oxygen Species|||Autophagy|||JNK
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