UB-221, CAS [[2755114-30-6]] Preis auf Anfrage

Produktübersicht

• Artikelname: UB-221, CAS [[2755114-30-6]] Preis auf Anfrage
• Artikelnummer: TGM-T9901A-1750
• Hersteller Artikelnummer: T9901A-1750
• Alternativnummer: TGM-T9901A-1750-1MG,TGM-T9901A-1750-5MG
• Hersteller: TargetMol
• Kategorie: Biochemikalien

Produktbeschreibung

UB-221 is a humanized IgG1 monoclonal antibody inhibitor that targets IgE. It significantly reduces IgE synthesis by stabilizing the membrane-bound CD23 on B lymphocytes and inhibits FcԑRI-mediated activation and degranulation of basophils. UB-221 lowers IgE levels in cynomolgus monkeys and human IgE (epsilon, kappa) transgenic (hIGHE knock-in) mice, making it relevant for asthma and chronic spontaneous urticaria (CSU) research.

Produkteigenschaften

• CAS Nummer: [2755114-30-6]
• Target-Kategorie: Others