Zaptuzumab, CAS [[2378046-35-4]] Preis auf Anfrage
Artikelnummer:
TGM-T9901A-1802
Hersteller Artikelnummer:
T9901A-1802
Alternativnummer:
TGM-T9901A-1802-1MG,TGM-T9901A-1802-5MG
Hersteller:
TargetMol
Kategorie:
Biochemikalien
Alternative Synonym:
AD5-10
Zaptuzumab (AD5-10) is a humanized monoclonal antibody targeting death receptor 5 (DR5) with high selective binding affinity. It specifically induces cancer cell death through caspase-mediated apoptosis and autophagic cell death (ACD). Zaptuzumab can activate antibody-dependent cell-mediated cytotoxicity (ADCC) and complement-dependent cytotoxicity (CDC). Additionally, it induces reactive oxygen species (ROS) production and reduces glutathione (GSH) levels. In various xenograft mouse tumor models, Zaptuzumab has demonstrated significant tumor growth inhibition and favorable safety profiles.
