Wilms tumor protein/WT1 Protein, Human, Recombinant (His & SUMO)

Artikelnummer: TGM-TMPH-02312
Artikelname: Wilms tumor protein/WT1 Protein, Human, Recombinant (His & SUMO)
Artikelnummer: TGM-TMPH-02312
Hersteller Artikelnummer: TMPH-02312
Alternativnummer: TGM-TMPH-02312-1MG,TGM-TMPH-02312-5UG,TGM-TMPH-02312-10UG,TGM-TMPH-02312-20UG,TGM-TMPH-02312-50UG,TGM-TMPH-02312-100UG,TGM-TMPH-02312-200UG,TGM-TMPH-02312-500UG
Hersteller: TargetMol
Kategorie: Biochemikalien
Alternative Synonym: Wilms tumor protein , WT33 , WT1
Transcription factor that plays an important role in cellular development and cell survival. Recognizes and binds to the DNA sequence 5-GCG(T/G)GGGCG-3. Regulates the expression of numerous target genes, including EPO. Plays an essential role for development of the urogenital system. It has a tumor suppressor as well as an oncogenic role in tumor formation. Function may be isoform-specific: isoforms lacking the KTS motif may act as transcription factors. Isoforms containing the KTS motif may bind mRNA and play a role in mRNA metabolism or splicing. Isoform 1 has lower affinity for DNA, and can bind RNA.
Molekulargewicht: 65.2 kDa (predicted)
TMPH-02312