LRRC32 Protein, Human, Recombinant (hFc)

Produktübersicht

• Artikelname: LRRC32 Protein, Human, Recombinant (hFc)
• Artikelnummer: TGM-TMPJ-00364
• Hersteller Artikelnummer: TMPJ-00364
• Alternativnummer: TGM-TMPJ-00364-1MG,TGM-TMPJ-00364-5UG,TGM-TMPJ-00364-10UG,TGM-TMPJ-00364-20UG,TGM-TMPJ-00364-50UG,TGM-TMPJ-00364-100UG,TGM-TMPJ-00364-200UG,TGM-TMPJ-00364-500UG
• Hersteller: TargetMol
• Kategorie: Biochemikalien
• Alternative Synonym: D11S833E , GARPGarpin , GARP , Garpin

Produktbeschreibung

Leucine Rich Repeat Containing 32 (LRRC32), also known as Glycoprotein A Repetitions Predominant (GARP), has been postulated as a novel surface marker of activated T(regs). LRRC32 binds directly to the TGF-beta latency associated peptide (LAP) and tethers latent TGF-beta on the surface of activated Treg cells. The presentation of TGF-beta on Tregs contributes to their ability to suppress naive T cell proliferation. LRRC32 is widely expressed during embryogenesis and on adult platelets. Human LRRC32 is identified as a lineage specific key receptor for human T cells.

Bilder

TMPJ-00364