LRRC32 Protein, Human, Recombinant (hFc)

Product Overview

• Article Name: LRRC32 Protein, Human, Recombinant (hFc)
• Biozol Catalog Number: TGM-TMPJ-00364
• Supplier Catalog Number: TMPJ-00364
• Alternative Catalog Number: TGM-TMPJ-00364-1MG,TGM-TMPJ-00364-5UG,TGM-TMPJ-00364-10UG,TGM-TMPJ-00364-20UG,TGM-TMPJ-00364-50UG,TGM-TMPJ-00364-100UG,TGM-TMPJ-00364-200UG,TGM-TMPJ-00364-500UG
• Manufacturer: TargetMol
• Category: Biochemikalien
• Alternative Names: D11S833E , GARPGarpin , GARP , Garpin

Product Description

Leucine Rich Repeat Containing 32 (LRRC32), also known as Glycoprotein A Repetitions Predominant (GARP), has been postulated as a novel surface marker of activated T(regs). LRRC32 binds directly to the TGF-beta latency associated peptide (LAP) and tethers latent TGF-beta on the surface of activated Treg cells. The presentation of TGF-beta on Tregs contributes to their ability to suppress naive T cell proliferation. LRRC32 is widely expressed during embryogenesis and on adult platelets. Human LRRC32 is identified as a lineage specific key receptor for human T cells.

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TMPJ-00364