DFF45 Protein, Human, Recombinant (His)

Artikelnummer: TGM-TMPJ-00483
Artikelname: DFF45 Protein, Human, Recombinant (His)
Artikelnummer: TGM-TMPJ-00483
Hersteller Artikelnummer: TMPJ-00483
Alternativnummer: TGM-TMPJ-00483-1MG,TGM-TMPJ-00483-5UG,TGM-TMPJ-00483-10UG,TGM-TMPJ-00483-20UG,TGM-TMPJ-00483-50UG,TGM-TMPJ-00483-100UG,TGM-TMPJ-00483-200UG,TGM-TMPJ-00483-500UG
Hersteller: TargetMol
Kategorie: Biochemikalien
Alternative Synonym: DNA Fragmentation Factor Subunit Alpha , DFF45 , H13 , ICAD , DFFA , DFF1 , DNA Fragmentation Factor Subunit alpha , DNA Fragmentation Factor 45 kDa Subunit , DFF-45 , Inhibitor of CAD
DNA Fragmentation Factor Subunit Alpha (DFFA). DFFA exists as a heterodimer (DFF) with DFFB. DFF is activated once DFFA is cleaved by Caspase-3. The cleaved fragments of DFFA detach from DFFB (the active component of DFF), which in turn triggers DNA fragmentation as well as chromatin condensation during apoptosis. A reduced level of DFFA detected in ovarian endometriosis may be a part of an apoptosis-resistant mechanism enhancing the disease progression.
TMPJ-00483