4-methoxylonchocarpin was isolated from the roots of Abrus precatorius as a potent anti-inflammatory compound. 4-methoxylonchocarpin inhibited NF-kappaB-activated TNF expression by inhibiting the binding of LPS to TLR4 in macrophages and suppressed TNBS-induced colitis in mice.
Molekulargewicht:
336.38
Reinheit:
98.00%
CAS Nummer:
[51589-67-4]
Formel:
C21H20O4
Target-Kategorie:
TNF|||NF-kappaB|||TLR|||Interleukin
TN7235
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