4-methoxylonchocarpin was isolated from the roots of Abrus precatorius as a potent anti-inflammatory compound. 4-methoxylonchocarpin inhibited NF-kappaB-activated TNF expression by inhibiting the binding of LPS to TLR4 in macrophages and suppressed TNBS-induced colitis in mice.
Molecular Weight:
336.38
Purity:
98.67%
CAS Number:
[51589-67-4]
Formula:
C21H20O4
Target:
TLR|||NF-kappaB|||TNF|||Interleukin
TN7235
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