KYL acetate is an EphA4 receptor tyrosine kinase inhibitor (Kd = 0.8 µM), inhibits EphA4-EphrinA5 interactions (IC50 = 6.34 µM). Prevents AbetaO induced synaptic damage, dendritic spine loss and prevents the blocking of LTP in hippocampal CA3-CA1 transmissions. Exhibits a long half life in cell culture media (8 and 12 hours in PC3 and C2C12 media respectively). Neuroprotective.
Molekulargewicht:
1525.78
Reinheit:
99.75%
Formel:
C76H112N14O19
Target-Kategorie:
Ephrin Receptor
TP1895L1
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
