Selective, high affinity, non-competitive alpha1A adrenoceptor antagonist (Ki = 0.35 nM). Exhibits no significant activity against a range of other GPCRs, including alpha2A, beta1 and beta2 adrenoceptors. Antagonizes effects of phenylephrine on isolated rabbit prostate muscle in vitro and on intra-urethral pressure in rats.
Molekulargewicht:
7283.22
Formel:
C310H481N87O100S8
Target-Kategorie:
Adrenergic Receptor
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
