cyclo(CLLFVY), CAS [[1446322-73-1]] Preis auf Anfrage

Produktübersicht

• Artikelname: cyclo(CLLFVY), CAS [[1446322-73-1]] Preis auf Anfrage
• Artikelnummer: TGM-TP2717
• Hersteller Artikelnummer: TP2717
• Alternativnummer: TGM-TP2717-10MG, TGM-TP2717-50MG
• Hersteller: TargetMol
• Kategorie: Biochemikalien

Produktbeschreibung

Cyclo(CLLFVY) is an inhibitor of hypoxia-inducible factor-1 (HIF-1), exhibiting half-maximal inhibitory concentrations (IC50) of 19 µM in U2OS cells and 16 µM in MCF-7 cells. It binds to the PAS-B domain of HIF-1alpha, inhibiting the dimerization and transcriptional activity of HIF-1. Moreover, cyclo(CLLFVY) downregulates the expression of hypoxia response genes (such as VEGF and CAIX), demonstrating antitumor effects against HIF-1-related cancers.

Produkteigenschaften

• Molekulargewicht: 738.94
• CAS Nummer: [1446322-73-1]
• Formel: C38H54N6O7S
• Target-Kategorie: HIF/HIF Prolyl-Hydroxylase|||VEGFR

Bilder

TP2717