cyclo(CLLFVY), CAS [[1446322-73-1]] Preis auf Anfrage

Product Overview

• Article Name: cyclo(CLLFVY), CAS [[1446322-73-1]] Preis auf Anfrage
• Biozol Catalog Number: TGM-TP2717
• Supplier Catalog Number: TP2717
• Alternative Catalog Number: TGM-TP2717-10MG, TGM-TP2717-50MG
• Manufacturer: TargetMol
• Category: Biochemikalien

Product Description

Cyclo(CLLFVY) is an inhibitor of hypoxia-inducible factor-1 (HIF-1), exhibiting half-maximal inhibitory concentrations (IC50) of 19 µM in U2OS cells and 16 µM in MCF-7 cells. It binds to the PAS-B domain of HIF-1alpha, inhibiting the dimerization and transcriptional activity of HIF-1. Moreover, cyclo(CLLFVY) downregulates the expression of hypoxia response genes (such as VEGF and CAIX), demonstrating antitumor effects against HIF-1-related cancers.

Product Properties

• Molecular Weight: 738.94
• CAS Number: [1446322-73-1]
• Formula: C38H54N6O7S
• Target: HIF/HIF Prolyl-Hydroxylase|||VEGFR

Images

TP2717