VSLRGDTRG is a synthetic peptide derived from the RGD motif in cadherin17 (CDH17) that binds to the alpha2beta1 integrin, activating its signaling pathways. By promoting high-affinity conformational changes in beta1 integrins through the RGD motif, VSLRGDTRG enhances cell adhesion and the phosphorylation of FAK and ERK1/2, thereby driving tumor proliferation and metastasis. This peptide is useful for research on cancers expressing CDH17, such as colorectal and pancreatic cancer.
Molekulargewicht:
960.047
CAS Nummer:
[2027476-29-3]
Formel:
C38H69N15O14
Target-Kategorie:
ERK|||FAK|||Integrin
TP3241
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
