VSLRGDTRG is a synthetic peptide derived from the RGD motif in cadherin17 (CDH17) that binds to the alpha2beta1 integrin, activating its signaling pathways. By promoting high-affinity conformational changes in beta1 integrins through the RGD motif, VSLRGDTRG enhances cell adhesion and the phosphorylation of FAK and ERK1/2, thereby driving tumor proliferation and metastasis. This peptide is useful for research on cancers expressing CDH17, such as colorectal and pancreatic cancer.
Molecular Weight:
960.047
CAS Number:
[2027476-29-3]
Formula:
C38H69N15O14
Target:
ERK|||FAK|||Integrin
TP3241
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