N-Acetylgalactosaminyltransferase 1 Preis auf Anfrage
Artikelnummer:
TGM-TRP-00404
Hersteller Artikelnummer:
TRP-00404
Alternativnummer:
TGM-TRP-00404-10MG,TGM-TRP-00404-50MG
Hersteller:
TargetMol
Kategorie:
Biochemikalien
Alternative Synonym:
GALNT1
N-Acetylgalactosaminyltransferase 1 (GALNT1) is a glycosyltransferase that initiates mucin-type O-glycosylation by transferring alpha-GalNAc from UDP-GalNAc to serine (Ser) or threonine (Thr) residues in proteins. Overexpression of N-Acetylgalactosaminyltransferase 1 in gastric cancer enhances the aberrant O-glycosylation of CD44, activating the Wnt/beta-catenin signaling pathway and influencing the malignant behavior of gastric cancer cells. This enzyme plays a crucial role in cancer progression and metastasis by modifying the O-glycosylation of various glycoproteins such as mucin (MUC1), osteopontin (OPN), matrix metalloproteinase-14 (MMP14), and integrin alpha3.
Target-Kategorie:
Endogenous Metabolite|||Wnt/beta-catenin
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
