N-Acetylgalactosaminyltransferase 1 Preis auf Anfrage
Biozol Catalog Number:
TGM-TRP-00404
Supplier Catalog Number:
TRP-00404
Alternative Catalog Number:
TGM-TRP-00404-10MG,TGM-TRP-00404-50MG
Manufacturer:
TargetMol
Category:
Biochemikalien
Alternative Names:
GALNT1
N-Acetylgalactosaminyltransferase 1 (GALNT1) is a glycosyltransferase that initiates mucin-type O-glycosylation by transferring alpha-GalNAc from UDP-GalNAc to serine (Ser) or threonine (Thr) residues in proteins. Overexpression of N-Acetylgalactosaminyltransferase 1 in gastric cancer enhances the aberrant O-glycosylation of CD44, activating the Wnt/beta-catenin signaling pathway and influencing the malignant behavior of gastric cancer cells. This enzyme plays a crucial role in cancer progression and metastasis by modifying the O-glycosylation of various glycoproteins such as mucin (MUC1), osteopontin (OPN), matrix metalloproteinase-14 (MMP14), and integrin alpha3.
Target:
Endogenous Metabolite|||Wnt/beta-catenin
* VAT and and shipping costs not included. Errors and price changes excepted
