(Rac)-Vepdegestrant, CAS [[2229711-08-2]] Preis auf Anfrage

Produktübersicht

• Artikelname: (Rac)-Vepdegestrant, CAS [[2229711-08-2]] Preis auf Anfrage
• Artikelnummer: TGM-TYD-02806
• Hersteller Artikelnummer: TYD-02806
• Alternativnummer: TGM-TYD-02806-10MG,TGM-TYD-02806-50MG
• Hersteller: TargetMol
• Kategorie: Biochemikalien
• Alternative Synonym: (Rac)-ARV-471

Produktbeschreibung

(Rac)-Vepdegestrant is an isomer of Vepdegestrant. Vepdegestrant ((Rac)-ARV-471) is an orally active estrogen receptor PROTAC degrader used against breast cancer. It is a heterobifunctional molecule that facilitates the interaction between estrogen receptor alpha and the intracellular E3 ligase complex. Vepdegestrant induces ubiquitination and subsequent degradation of the estrogen receptor via the proteasome, effectively degrading ER in ER-positive breast cancer cell lines with a DC50 value of approximately 2 nM.

Produkteigenschaften

• Molekulargewicht: 723.9
• CAS Nummer: [2229711-08-2]
• Formel: C45H49N5O4
• Target-Kategorie: Estrogen Receptor/ERR|||PROTACs

Bilder

TYD-02806