(Rac)-Vepdegestrant, CAS [[2229711-08-2]] Preis auf Anfrage

Product Overview

• Article Name: (Rac)-Vepdegestrant, CAS [[2229711-08-2]] Preis auf Anfrage
• Biozol Catalog Number: TGM-TYD-02806
• Supplier Catalog Number: TYD-02806
• Alternative Catalog Number: TGM-TYD-02806-10MG,TGM-TYD-02806-50MG
• Manufacturer: TargetMol
• Category: Biochemikalien
• Alternative Names: (Rac)-ARV-471

Product Description

(Rac)-Vepdegestrant is an isomer of Vepdegestrant. Vepdegestrant ((Rac)-ARV-471) is an orally active estrogen receptor PROTAC degrader used against breast cancer. It is a heterobifunctional molecule that facilitates the interaction between estrogen receptor alpha and the intracellular E3 ligase complex. Vepdegestrant induces ubiquitination and subsequent degradation of the estrogen receptor via the proteasome, effectively degrading ER in ER-positive breast cancer cell lines with a DC50 value of approximately 2 nM.

Product Properties

• Molecular Weight: 723.9
• CAS Number: [2229711-08-2]
• Formula: C45H49N5O4
• Target: Estrogen Receptor/ERR|||PROTACs

Images

TYD-02806