(3S,4R)-ME-344, CAS [[1374524-84-1]] Preis auf Anfrage
Artikelnummer:
TGM-TYD-04011
Hersteller Artikelnummer:
TYD-04011
Alternativnummer:
TGM-TYD-04011-10MG, TGM-TYD-04011-50MG
Hersteller:
TargetMol
Kategorie:
Biochemikalien
(3S,4R)-ME-344 is the (3S,4R)-enantiomer of ME-344. As an inhibitor of mitochondrial heme oxygenase 1 (HO-1), ME-344 specifically binds to and alters the structure of HO-1, facilitating its translocation from the rough endoplasmic reticulum to mitochondria, but only in drug-sensitive cells like H460 and SHP-77. This compound reduces mitochondrial ATP production and induces reactive oxygen species (ROS), disrupting redox balance and mitochondrial function. ME-344 exhibits significant antitumor activity, making it useful in cancer research, such as for breast cancer.
Molekulargewicht:
348.39
CAS Nummer:
[1374524-84-1]
Formel:
C22H20O4
Target-Kategorie:
Mitochondrial Metabolism|||ROS
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