(3S,4R)-ME-344, CAS [[1374524-84-1]] Preis auf Anfrage

Catalog Number: TGM-TYD-04011
Article Name: (3S,4R)-ME-344, CAS [[1374524-84-1]] Preis auf Anfrage
Biozol Catalog Number: TGM-TYD-04011
Supplier Catalog Number: TYD-04011
Alternative Catalog Number: TGM-TYD-04011-10MG, TGM-TYD-04011-50MG
Manufacturer: TargetMol
Category: Biochemikalien
(3S,4R)-ME-344 is the (3S,4R)-enantiomer of ME-344. As an inhibitor of mitochondrial heme oxygenase 1 (HO-1), ME-344 specifically binds to and alters the structure of HO-1, facilitating its translocation from the rough endoplasmic reticulum to mitochondria, but only in drug-sensitive cells like H460 and SHP-77. This compound reduces mitochondrial ATP production and induces reactive oxygen species (ROS), disrupting redox balance and mitochondrial function. ME-344 exhibits significant antitumor activity, making it useful in cancer research, such as for breast cancer.
Molecular Weight: 348.39
CAS Number: [1374524-84-1]
Formula: C22H20O4
Target: Mitochondrial Metabolism|||ROS