CDDO Methyl Ester is a synthetic triterpenoid that inhibits IkappaBalpha kinase and enhances apoptosis induced by TNF and chemotherapeutic agents through down-regulation of expression of nuclear factor kappaB-regulated gene products in human leukemic cells. CDDO Methyl Ester is a novel therapeutic agent in the treatment of acute myeloid leukemia and in the treatment of pancreatic cancer as well as other forms of cancer. Form: White to Off-White Solid Melting Point: 215-219C Solubility: Chloroform, Methanol (Sparingly)
Molekulargewicht:
505.69
Formulierung:
White to Off-White Solid
CAS Nummer:
[218600-53-4]
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