AF353 (P2X3 Purinergic Receptor Antagonist, AF353, P2X2/3 Purinergic Receptor Antagonist, AF353), CAS [[927887-18-1]]

Produktübersicht

• Artikelname: AF353 (P2X3 Purinergic Receptor Antagonist, AF353, P2X2/3 Purinergic Receptor Antagonist, AF353), CAS [[927887-18-1]]
• Artikelnummer: USB-217162
• Hersteller Artikelnummer: 217162
• Alternativnummer: USB-217162-5
• Hersteller: US Biological
• Kategorie: Biochemikalien

Produktbeschreibung

A novel, potent, orally bioavailable antagonist of P2X3/P2X2/3 receptors (pIC50 = 8 in human and rat, pIC50 = 7.3 for human P2X2/3 receptor). Shown to be highly brain penetrant with a brain to plasma ratio of 6. Blocks agonist-evoked intracellular Ca2+ f

Produkteigenschaften

• Reinheit: 99% (HPLC)
• Formulierung: Supplied as a light brown powder.
• CAS Nummer: [927887-18-1]