Bicuculline (GABAA Receptor Antagonist, (+)-Bicuculline), CAS [[485-49-4]]

Artikelnummer: USB-217220
Artikelname: Bicuculline (GABAA Receptor Antagonist, (+)-Bicuculline), CAS [[485-49-4]]
Artikelnummer: USB-217220
Hersteller Artikelnummer: 217220
Alternativnummer: USB-217220-50,USB-217220-100,USB-217220-250,USB-217220-500
Hersteller: US Biological
Kategorie: Biochemikalien
A potent allosteric antagonist of vertebrate GABAA receptors. Blocks GABAA-induced chloride currents in cultured neurons (IC50 = 740nM). Shown to increase blood pressure in spontaneously hypertensive rats and cause convulsion in experimental animals. Also, increases the amplitude of spontaneous colonic contractions. CAS No: 485-49-4 Molecular Formula: C20H17NO6 Molecular Weight: 367.35 Appearance: Pale yellow solid Purity: 99% (HPLC) Melting Point: 193-197C (lit) Primary Target: GABA-A Primary Target IC50: 740Nm Solubility: DMSO Elemental Analysis: C: 64-66%, H: 4-5.5%, N: 3-5% Water by CHN (mol): 1.0mol Optical Rotation: +130-145 Storage and Stability: Powder is stable for 6 months after receipt at 4C. Hygroscopic. Under inert atmosphere.
Molekulargewicht: 367.35
Reinheit: 98% (HPLC)
Formulierung: Pale yellow solid
CAS Nummer: [485-49-4]