Bicuculline (GABAA Receptor Antagonist, (+)-Bicuculline), CAS [[485-49-4]]
Catalog Number:
USB-217220
| Article Name: |
Bicuculline (GABAA Receptor Antagonist, (+)-Bicuculline), CAS [[485-49-4]] |
| Biozol Catalog Number: |
USB-217220 |
| Supplier Catalog Number: |
217220 |
| Alternative Catalog Number: |
USB-217220-50,USB-217220-100,USB-217220-250,USB-217220-500 |
| Manufacturer: |
US Biological |
| Category: |
Biochemikalien |
| A potent allosteric antagonist of vertebrate GABAA receptors. Blocks GABAA-induced chloride currents in cultured neurons (IC50 = 740nM). Shown to increase blood pressure in spontaneously hypertensive rats and cause convulsion in experimental animals. Also, increases the amplitude of spontaneous colonic contractions. CAS No: 485-49-4 Molecular Formula: C20H17NO6 Molecular Weight: 367.35 Appearance: Pale yellow solid Purity: 99% (HPLC) Melting Point: 193-197C (lit) Primary Target: GABA-A Primary Target IC50: 740Nm Solubility: DMSO Elemental Analysis: C: 64-66%, H: 4-5.5%, N: 3-5% Water by CHN (mol): 1.0mol Optical Rotation: +130-145 Storage and Stability: Powder is stable for 6 months after receipt at 4C. Hygroscopic. Under inert atmosphere. |
| Molecular Weight: |
367.35 |
| Purity: |
98% (HPLC) |
| Form: |
Pale yellow solid |
| CAS Number: |
[485-49-4] |
