CRADD, Recombinant, Human, aa1-199, His-SUMO-Tag (Death Domain-containing Protein CRADD)
Artikelnummer:
USB-372860
Hersteller Artikelnummer:
372860
Alternativnummer:
USB-372860-20,USB-372860-100,USB-372860-1
Hersteller:
US Biological
Kategorie:
Molekularbiologie
Apoptotic adaptor molecule specific for caspase-2 and FASL/TNF receptor-interacting protein RIP. In the presence of RIP and TRADD, CRADD recruits caspase-2 to the TNFR-1 signalling complex. Source: Recombinant protein corresponding to aa1-99 from human Death Domain-containing Protein CRADD fused to His-SUMO-Tag at N-terminal expressed in E. coli. Molecular Weight: ~38.7kD Amino Acid Sequence: MEARDKQVLRSLRLELGAEVLVEGLVLQYLYQEGILTENHIQEINAQTTGLRKTMLLLDILPSRGPKAFDTFLDSLQEFPWVREKLKKAREEAMTDLPAGDRLTGIPSHILNSSPSDRQINQLAQRLGPEWEPMVLSLGLSQTDIYRCKANHPHNVQSQVVEAFIRWRQRFGKQATFQSLHNGLRAVEVDPSLLLHMLE Storage and Stability: Lyophilized and reconstituted products are stable for 6 months after receipt at -20C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Supplied as a lyophilized powder from 20mM Tris-HCl, 0.5M sodium chloride, pH 8.0, 6% trehalose. Reconstitute with sterile ddH2O to a concentration of 0.1-1mg/ml.
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