Dorsomorphin Dihydrochloride, CAS [[1219168-18-9]]
Artikelnummer:
USB-447668
Hersteller Artikelnummer:
447668
Alternativnummer:
USB-447668-10,USB-447668-50
Hersteller:
US Biological
Kategorie:
Biochemikalien
Dorsomorphin is an AMP-activated kinase (AMPK) inhibitor. Dorsomorphin selectively inhibits the bone morphogenetic protein (BMP) type I receptors ALK2, ALK3 and ALK6 and thus blocks BMP-mediated SMAD1/5/8 phosphorylation, target gene transcription and osteogenic differentiation. Dorsomorphin has shown to to increase cisplatin-induced apoptosis, which was associated with hyper-induction of the tumor suppressor p53. Molecular Formula: C24H27Cl2N5O Solubility: DMSO, Water Molecular Weight: 472.41 Storage and Stability: Store at -20C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molekulargewicht:
472.41
Formulierung:
Supplied as a Yellow Solid
CAS Nummer:
[1219168-18-9]
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