Dorsomorphin Dihydrochloride, CAS [[1219168-18-9]]

Artikelnummer: USB-447668
Artikelname: Dorsomorphin Dihydrochloride, CAS [[1219168-18-9]]
Artikelnummer: USB-447668
Hersteller Artikelnummer: 447668
Alternativnummer: USB-447668-10,USB-447668-50
Hersteller: US Biological
Kategorie: Biochemikalien
Dorsomorphin is an AMP-activated kinase (AMPK) inhibitor. Dorsomorphin selectively inhibits the bone morphogenetic protein (BMP) type I receptors ALK2, ALK3 and ALK6 and thus blocks BMP-mediated SMAD1/5/8 phosphorylation, target gene transcription and osteogenic differentiation. Dorsomorphin has shown to to increase cisplatin-induced apoptosis, which was associated with hyper-induction of the tumor suppressor p53. Molecular Formula: C24H27Cl2N5O Solubility: DMSO, Water Molecular Weight: 472.41 Storage and Stability: Store at -20C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molekulargewicht: 472.41
Formulierung: Supplied as a Yellow Solid
CAS Nummer: [1219168-18-9]