Dorsomorphin Dihydrochloride, CAS [[1219168-18-9]]

Product Overview

• Article Name: Dorsomorphin Dihydrochloride, CAS [[1219168-18-9]]
• Biozol Catalog Number: USB-447668
• Supplier Catalog Number: 447668
• Alternative Catalog Number: USB-447668-10,USB-447668-50
• Manufacturer: US Biological
• Category: Biochemikalien

Product Description

Dorsomorphin is an AMP-activated kinase (AMPK) inhibitor. Dorsomorphin selectively inhibits the bone morphogenetic protein (BMP) type I receptors ALK2, ALK3 and ALK6 and thus blocks BMP-mediated SMAD1/5/8 phosphorylation, target gene transcription and osteogenic differentiation. Dorsomorphin has shown to to increase cisplatin-induced apoptosis, which was associated with hyper-induction of the tumor suppressor p53. Molecular Formula: C24H27Cl2N5O Solubility: DMSO, Water Molecular Weight: 472.41 Storage and Stability: Store at -20C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Product Properties

• Molecular Weight: 472.41
• Form: Supplied as a Yellow Solid
• CAS Number: [1219168-18-9]