TLR12 (Toll-like Receptor 12, Gm1365), IgM, Clone: [11E379], Mouse, Monoclonal

Artikelnummer: USB-T8051-21
Artikelname: TLR12 (Toll-like Receptor 12, Gm1365), IgM, Clone: [11E379], Mouse, Monoclonal
Artikelnummer: USB-T8051-21
Hersteller Artikelnummer: T8051-21
Alternativnummer: USB-T8051-21-200
Hersteller: US Biological
Wirt: Mouse
Kategorie: Antikörper
Applikation: WB
Immunogen: Synthetic peptide corresponding to aa791-821 of mouse TLR12.
The Toll-like receptor (TLR) family in mammal comprises a family of transmembrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and IL-1 receptor motif in the cytoplasmic domain. Like its counterparts in Drosophila, TLRs signal through adaptor molecules (1). The TLR family is a phylogenetically conserved mediator of innate immunity that is essential for microbial recognition (2). TLR12 has been cloned that displays a distinct pattern of expression in macrophages and liver, kidney, and bladder epithelial cells. TLR12 does not respond to known TLR ligands. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1:1000 Optimal dilutions to be determined by the researcher. Positive Control: Transfected cell lysate Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Klonalität: Monoclonal
Klon-Bezeichnung: [11E379]
Isotyp: IgM
NCBI: 991392
UniProt: Q6QNU9
Reinheit: Ascites
Formulierung: Supplied as a liquid in PBS, 0.2% gelatin, 0.05% sodium azide.