TLR12 (Toll-like Receptor 12, Gm1365), IgM, Clone: [11E379], Mouse, Monoclonal
Catalog Number:
USB-T8051-21
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| Article Name: | TLR12 (Toll-like Receptor 12, Gm1365), IgM, Clone: [11E379], Mouse, Monoclonal |
| Biozol Catalog Number: | USB-T8051-21 |
| Supplier Catalog Number: | T8051-21 |
| Alternative Catalog Number: | USB-T8051-21-200 |
| Manufacturer: | US Biological |
| Host: | Mouse |
| Category: | Antikörper |
| Application: | WB |
| Immunogen: | Synthetic peptide corresponding to aa791-821 of mouse TLR12. |
| The Toll-like receptor (TLR) family in mammal comprises a family of transmembrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and IL-1 receptor motif in the cytoplasmic domain. Like its counterparts in Drosophila, TLRs signal through adaptor molecules (1). The TLR family is a phylogenetically conserved mediator of innate immunity that is essential for microbial recognition (2). TLR12 has been cloned that displays a distinct pattern of expression in macrophages and liver, kidney, and bladder epithelial cells. TLR12 does not respond to known TLR ligands. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1:1000 Optimal dilutions to be determined by the researcher. Positive Control: Transfected cell lysate Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. |
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