aryl hydrocarbon receptor nuclear translocator Adenovirus (Ad-HIF1b/ARNT)

Produktübersicht

• Artikelname: aryl hydrocarbon receptor nuclear translocator Adenovirus (Ad-HIF1b/ARNT)
• Artikelnummer: VBL-1444
• Hersteller Artikelnummer: 1444
• Alternativnummer: VBL-1444
• Hersteller: Vector Biolabs
• Kategorie: Sonstiges
• Alternative Synonym: aryl hydrocarbon receptor nuclear translocator Adenovirus

Produktbeschreibung

The aryl hydrocarbon (Ah) receptor is involved in the induction of several enzymes that participate in xenobiotic metabolism. The ligand-free, cytosolic form of the Ah receptor is complexed to heat shock protein 90. Binding of ligand, which includes dioxin and polycyclic aromatic hydrocarbons, results in translocation of the ligand-binding subunit only to the nucleus. Induction of enzymes involved in xenobiotic metabolism occurs through binding of the ligand-bound Ah receptor to xenobiotic responsive elements in the promoters of genes for these enzymes. This gene encodes a protein that forms a complex with the ligand-bound Ah receptor, and is required for receptor function. The encoded protein has also been identified as the beta subunit of a heterodimeric transcription factor, hypoxia-inducible factor 1 (HIF1)

Produkteigenschaften

• Konzentration: 1x10 10 PFU/ml
• Puffer: DMEM, 2% BSA, 2.5% Glycerol

Bilder