aryl hydrocarbon receptor nuclear translocator Adenovirus (Ad-HIF1b/ARNT)
Catalog Number:
VBL-1444
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| Article Name: | aryl hydrocarbon receptor nuclear translocator Adenovirus (Ad-HIF1b/ARNT) |
| Biozol Catalog Number: | VBL-1444 |
| Supplier Catalog Number: | 1444 |
| Alternative Catalog Number: | VBL-1444 |
| Manufacturer: | Vector Biolabs |
| Category: | Sonstiges |
| Alternative Names: | aryl hydrocarbon receptor nuclear translocator Adenovirus |
| The aryl hydrocarbon (Ah) receptor is involved in the induction of several enzymes that participate in xenobiotic metabolism. The ligand-free, cytosolic form of the Ah receptor is complexed to heat shock protein 90. Binding of ligand, which includes dioxin and polycyclic aromatic hydrocarbons, results in translocation of the ligand-binding subunit only to the nucleus. Induction of enzymes involved in xenobiotic metabolism occurs through binding of the ligand-bound Ah receptor to xenobiotic responsive elements in the promoters of genes for these enzymes. This gene encodes a protein that forms a complex with the ligand-bound Ah receptor, and is required for receptor function. The encoded protein has also been identified as the beta subunit of a heterodimeric transcription factor, hypoxia-inducible factor 1 (HIF1) |
| Concentration: | 1x10 10 PFU/ml |
| Buffer: | DMEM, 2% BSA, 2.5% Glycerol |
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