Down syndrome critical region gene 1 Adenovirus (Ad-DSCR1)

Artikelnummer: VEB-1539
Artikelname: Down syndrome critical region gene 1 Adenovirus (Ad-DSCR1)
Artikelnummer: VEB-1539
Hersteller Artikelnummer: 1539
Alternativnummer: VEB-1539
Hersteller: VectorBuilder
Kategorie: Molekularbiologie
Alternative Synonym: Down syndrome critical region gene 1 Adenovirus
The protein encoded by this gene interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease.
Puffer: DMEM, 2% BSA, 2.5% Glycerol