Down syndrome critical region gene 1 Adenovirus (Ad-DSCR1)

Product Overview

• Article Name: Down syndrome critical region gene 1 Adenovirus (Ad-DSCR1)
• Biozol Catalog Number: VEB-1539
• Supplier Catalog Number: 1539
• Alternative Catalog Number: VEB-1539
• Manufacturer: VectorBuilder
• Category: Molekularbiologie
• Alternative Names: Down syndrome critical region gene 1 Adenovirus

Product Description

The protein encoded by this gene interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease.

Product Properties

• Buffer: DMEM, 2% BSA, 2.5% Glycerol