Hypoxia-inducible factor 1, alpha subunit inhibitor Adenovirus (Ad-HIF1AN/FIH1)

Produktübersicht

• Artikelname: Hypoxia-inducible factor 1, alpha subunit inhibitor Adenovirus (Ad-HIF1AN/FIH1)
• Artikelnummer: VEB-1551
• Hersteller Artikelnummer: 1551
• Alternativnummer: VEB-1551
• Hersteller: VectorBuilder
• Kategorie: Molekularbiologie
• Alternative Synonym: Hypoxia-inducible factor 1, alpha subunit inhibitor Adenovirus

Produktbeschreibung

Factor inhibiting HIF-1 (FIH-1) exists as a homodimer and binds to HIF-1-alpha. Specifically, FIH-1 operates as an asparaginyl hydroxylase and catalyzes the hydroxylation of the beta-carbon of asparagine residue 803 within the C-terminal transactivation domain of HIF-1-alpha. This hyroxylation event blocks the association of HIF-1alpha with coactivators.

Produkteigenschaften

• Puffer: DMEM, 2% BSA, 2.5% Glycerol