Hypoxia-inducible factor 1, alpha subunit inhibitor Adenovirus (Ad-HIF1AN/FIH1)

Product Overview

• Article Name: Hypoxia-inducible factor 1, alpha subunit inhibitor Adenovirus (Ad-HIF1AN/FIH1)
• Biozol Catalog Number: VEB-1551
• Supplier Catalog Number: 1551
• Alternative Catalog Number: VEB-1551
• Manufacturer: VectorBuilder
• Category: Molekularbiologie
• Alternative Names: Hypoxia-inducible factor 1, alpha subunit inhibitor Adenovirus

Product Description

Factor inhibiting HIF-1 (FIH-1) exists as a homodimer and binds to HIF-1-alpha. Specifically, FIH-1 operates as an asparaginyl hydroxylase and catalyzes the hydroxylation of the beta-carbon of asparagine residue 803 within the C-terminal transactivation domain of HIF-1-alpha. This hyroxylation event blocks the association of HIF-1alpha with coactivators.

Product Properties

• Buffer: DMEM, 2% BSA, 2.5% Glycerol