Diablo homolog (Drosophila) Adenovirus (Ad-DIABLO)

Artikelnummer: VEB-1587
Artikelname: Diablo homolog (Drosophila) Adenovirus (Ad-DIABLO)
Artikelnummer: VEB-1587
Hersteller Artikelnummer: 1587
Alternativnummer: VEB-1587
Hersteller: VectorBuilder
Kategorie: Molekularbiologie
Alternative Synonym: Diablo homolog (Drosophila) Adenovirus
Smac (for second mitochondria-derived activator of caspase, also designated DIABLO in mouse for direct IAP [inhibitor of apoptosis protein] binding protein with low PI) promotes caspase activation in the cytochrome c/Apaf-1/caspase-9 pathway by binding IAPs and removing their inhibitory activity. In healthy cells, Smac resides in the mitochondria, but when cells undergo apoptosis, Smac is released into the cytosol.
Puffer: DMEM, 2% BSA, 2.5% Glycerol