Diablo homolog (Drosophila) Adenovirus (Ad-DIABLO)

Catalog Number: VEB-1587
Article Name: Diablo homolog (Drosophila) Adenovirus (Ad-DIABLO)
Biozol Catalog Number: VEB-1587
Supplier Catalog Number: 1587
Alternative Catalog Number: VEB-1587
Manufacturer: VectorBuilder
Category: Molekularbiologie
Alternative Names: Diablo homolog (Drosophila) Adenovirus
Smac (for second mitochondria-derived activator of caspase, also designated DIABLO in mouse for direct IAP [inhibitor of apoptosis protein] binding protein with low PI) promotes caspase activation in the cytochrome c/Apaf-1/caspase-9 pathway by binding IAPs and removing their inhibitory activity. In healthy cells, Smac resides in the mitochondria, but when cells undergo apoptosis, Smac is released into the cytosol.
Buffer: DMEM, 2% BSA, 2.5% Glycerol