The incredible regulatory power of microRNAs (miRNAs) and other short non-coding RNA sequences (sncRNA) was discovered very recently. Research into these highly abundant RNAs revealed their crucial involvement in orchestration of all molecular signalling pathways (p53, Wnt, FAS and others) and their potential as a biomarker. The ability of miRNAs to immediately respond to path...

Join our partner GeneTex' upcoming webinar on inflammatory training and tissue repair. Inflammatory training is the generation of an epigenetic memory that leads to an augmented state of responsiveness to a broad range of secondary stimuli. Though previously thought to be exclusive to the innate immune system, Dr. Samantha Larsen discovered that epithelial stem cells can undergo inflammatory training that accelerates tissue repair. She revealed this phenomenon hinges on the coordinated efforts of stimulus-specific, stress-responsive, and...

Viral epidemics are one of the greatest challenges of our time. The causative agents of most viral infectious diseases that have occurred in recent decades are RNA viruses. In addition to SARS-CoV-2, these include influenza viruses, Ebola virus, poliovirus, Zika and dengue virus, among others. R...

One of the main features of Alzheimer's disease is the formation of senile plaques by extracellular deposits of beta-amyloid and intracellular fibrillar deposits in the gray matter of the brain. These are usually detected by light microscopy after silver staining or by immunofluorescence. Amytracker from our partner

Autophagy refers to the process of degradation and utilization of own cellular components such as misfolded proteins or organelles by eukaryotic cells. Autophagy in mammals is involved not only in the starvation response, but also in antigen presentation, cell death, development, aging, tumorigenesis, and defense against bacterial infections. Autophagy research is therefore important for understanding all these processes. LC3 has been studied extensively and is used as an autophagy marker in mammals. So...

Cardiovascular diseases are the most common cause of death worldwide and in Germany. However, if diagnosed in time, these diseases can usually be treated well. With our partners' high-quality ELISA kits for biomarker detection, we support your preclinical and clinical research on cardiovascular diseases.   FGF23: Novel Risk Marker of Heart Failure...

Diacylglycerol kinase (DGK or DAGK) is a family of enzymes that catalyze the conversion of diacylglycerol (DAG) to phosphatidic acid (PA) using ATP as the phosphate source. They serve as switches by terminating signal transduction of one lipid while activating signal transduction by another. SignalChem offers the complete set of DGKs expressed in SF9 cells either as GST- or His-tagged variants.  ...

Full and empty capsids of different Adeno-associated Virus serotypes commonly used for gene transfer     Recombinant Adeno-associated virus (rAAV) is a widely used gene delivery tool for research and clinical applications. To be able to compare the pharmacokinetics and efficacy of rAAV, well characterized reference materials are ne...

New recombinant Anti-Influenza A/B Antbodies from GeneTex   Influenza A and B viruses are two viruses that have caused seasonal influenza, epidemics, and even pandemic for Influenza A. GeneTex has released three clones each for Influenza A and B Nucleoproteins, the nucleoprotein is conserved in different variants therefore a suitable target for detecting the virus antigen.   The antibodies can work as ELISA pairs and showed a low picomolar range sensitivity

Add color to your image with the special staining solutions and kits for histology from ScyTek Laboratories Inc.   ready to use CE-IVD marked color intensive cost-efficient   In response to pathologists' desire for higher quality products and more reliable results, ScyTek began producing the specialty staining solutions in the mi...