SPP-037 is an orally active and selective inhibitor of ST6GAL1 (IC50: 3.59 µM). SPP-037 exhibits anti-MDA-MB-231 cell migration activity by inhibiting integrin alpha2,6-sialylation and integrin-FAK-paxillin pathway. SPP-037 has anti-tumor activity in MDA-MB-231 xenograft mouse model. SPP-037 can be used in breast cancer research[1].
Molecular Weight:
736.31
Formula:
C36H50ClN3O9S
Target:
Endogenous Metabolite,FAK
Application Notes:
MCE Product type: Reference compound
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