TC13172 is a potent, covalent, and selective MLKL inhibitor that blocks necroptosis with an EC50 of 2 nM in HT-29 cells. It prevents MLKL oligomerization and membrane translocation, making it a valuable chemical probe for studying necroptosis in inflammatory and degenerative disease research.
Molecular Weight:
388.4
CAS Number:
[2093393-05-4]
Formula:
C17H16N4O5S
Target:
MLK
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