(R)-AS-1 is a potent, selective positive allosteric modulator of EAAT2 (EC50 = 11 nM). It exhibits anticonvulsant efficacy in multiple mouse seizure models (MES, PTZ) and enhances locomotor activity, supporting its research application in studying EAAT2 function and neurological disorders like epilepsy.
Molecular Weight:
260.29
CAS Number:
[2506367-95-7]
Formula:
C14H16N2O3
Target:
transporter,Others
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