PARK2 (E3 Ubiquitin-Protein Ligase Parkin, Parkin RBR E3 Ubiquitin Protein Ligase), Rabbit

Catalog Number: USB-488056
Article Name: PARK2 (E3 Ubiquitin-Protein Ligase Parkin, Parkin RBR E3 Ubiquitin Protein Ligase), Rabbit
Biozol Catalog Number: USB-488056
Supplier Catalog Number: 488056
Alternative Catalog Number: USB-488056-100
Manufacturer: US Biological
Host: Rabbit
Category: Antikörper
Application: WB
Immunogen: Synthetic peptide corresponding to the middle region of human PARK2
The precise function of this gene is unknown, however, the encoded protein is a component of a multiprotein E3 ubiquitin ligase complex that mediates the targeting of substrate proteins for proteasomal degradation. Mutations in this gene are known to cause Parkinson disease and autosomal recessive juvenile Parkinson disease. Alternative splicing of this gene produces multiple transcript variants encoding distinct isoforms. Additional splice variants of this gene have been described but currently lack transcript support. [provided by RefSeq, Jul 2008] Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
NCBI: 004553
UniProt: O60260
Purity: Purified by affinity chromatography.
Form: Supplied as a liquid in PBS, 2% sucrose, 0.09% sodium azide.