TYK2 (Non-Receptor Tyrosine-Protein Kinase TYK2, Tyrosine Kinase 2), Rabbit

Catalog Number: USB-494953
Article Name: TYK2 (Non-Receptor Tyrosine-Protein Kinase TYK2, Tyrosine Kinase 2), Rabbit
Biozol Catalog Number: USB-494953
Supplier Catalog Number: 494953
Alternative Catalog Number: USB-494953-100
Manufacturer: US Biological
Host: Rabbit
Category: Antikörper
Application: WB
Immunogen: Synthetic peptide corresponding to the C-terminal region of human TYK2
This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
NCBI: 003322
UniProt: P29597
Purity: Purified by affinity chromatography.
Form: Supplied as a liquid in PBS, 2% sucrose, 0.09% sodium azide.